Pharmacokinetic Study of Nifedipine in Healthy Adult Male Human Volunteers
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چکیده
منابع مشابه
Pharmacokinetic interaction between amprenavir and clarithromycin in healthy male volunteers.
The P450 enzyme, CYP3A4, extensively metabolizes both amprenavir and clarithromycin. To determine if an interaction exists when these two drugs are coadministered, the pharmacokinetics of amprenavir and clarithromycin were investigated in healthy adult male volunteers. This was a Phase I, open-label, randomized, balanced, multiple-dose, three-period crossover study. Fourteen subjects received t...
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Erythromycin is an antibiotic useful for the treatment of a number of bacterial infections. This includes respiratory tract infections, skin infections, chlamydia infections, and syphilis. It may also be used during pregnancy to prevent Group B streptococcal infection in newborns [1]. It is an effective inhibitor of CYP3A4 that patently increases circulating levels of some other HMG-CoA reducta...
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BACKGROUND Ranitidine is a histamine 2 receptor antagonist, and daijokito is a Kampo (Chinese herbal medicine as practiced in Japan) formula, which is traditionally used for treating constipation and digestive trouble. Previous study demonstrated that daijokito significantly affected the pharmacokinetics of ranitidine in rats; however, the doses of ranitidine and daijokito in that study were hi...
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ژورنال
عنوان ژورنال: Tropical Journal of Pharmaceutical Research
سال: 2009
ISSN: 1596-9827,1596-5996
DOI: 10.4314/tjpr.v8i5.48093